Ordering Recommendation

Fetal genotyping to assess risk for alloimmune thrombocytopenia. For parental or neonatal testing, refer to Platelet Antigen Genotyping Panel (3000193).

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Amniotic fluid
OR cultured amniocytes OR cultured CVS: Two T-25 flasks at 80 percent confluency.
AND whole blood for maternal cell contamination: lavender (EDTA), pink (K2EDTA), or yellow (ACD solution A or B)

If the client is unable to culture, order test Cytogenetics Grow and Send (ARUP test code 0040182) in addition to this test and ARUP will culture upon receipt (culturing fees will apply). If you have any questions, contact ARUP's Genetics Processing at 800-522-2787 ext. 3301.

Specimen Preparation

Amniotic fluid: Transport 10 mL amniotic fluid in a sterile container. (Min: 5 mL)
OR cultured amniocytes OR cultured CVS: Fill flasks with culture media. Backup cultures must be retained at the client's institution until testing is complete.
Whole blood for maternal cell contamination: Transport 3 mL whole blood. (Min: 1 mL)

Storage/Transport Temperature

Amniotic fluid, cultured amniocytes, cultured CVS: CRITICAL TEMPERATURE. Must be received within 48 hours of shipment due to lability of cells.
Whole blood for maternal cell contamination: Refrigerated.

Unacceptable Conditions

Frozen specimens in glass collection tubes.

Remarks

The Patient History Form is available on the ARUP website or by contacting ARUP Client Services.

Stability

Fetal specimens: Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable
Whole blood for maternal cell contamination: Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month

Methodology

Polymerase Chain Reaction (PCR)/Fluorescence Monitoring/Fragment Analysis

Performed

Varies

Reported

7-14 days

Reference Interval

Interpretive Data

Refer to report.

Compliance Category

Modified FDA

Note

Hotline History

N/A

CPT Codes

81105; 81106; 81107; 81108; 81109; 81110; 81112; 81265 Fetal Cell Contamination (FCC)

Components

Component Test Code* Component Chart Name LOINC
0050548 Maternal Contamination Study Fetal Spec 59266-7
0050612 Maternal Contam Study, Maternal Spec 66746-9
3001173 Platelet Antigen 1 Genotyping
3001174 Platelet Antigen 2 Genotyping
3001175 Platelet Antigen 3 Genotyping
3001176 Platelet Antigen 4 Genotyping
3001177 Platelet Antigen 5 Genotyping
3001178 Platelet Antigen 6 Genotyping
3001179 Platelet Antigen 15 Genotyping
3016674 Platelet Antigen Geno Fetal, Interp
3016675 Platelet Antigen Geno, Fetal Specimen
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • HPA platelet antigen genotyping panel
Platelet Antigen Genotyping Panel, Fetal